Context of the research: Research is increasingly carried out to take into account the social behavior of residents, the type of industry located in the area, and perceived preference for the place of residence. The quality of life in urban space is increasingly seen as a problem of cooperation between various stakeholders. These studies not only identify factors and sources of odor emissions, but also serve as the basis for creating systems to alert people living in areas adjacent to industrial areas or harmful and unpleasant industrial emissions. In recent years, environmental issues, particularly unpleasant sensory experiences, have been one of the most important acceptance criteria. Aim of the article: The aim of the study is to assess the impact of odor nuisance in the south-eastern part of Kraków (Płaszów) on the residents’ decision to leave their place of residence. In particular, the research goal was achieved to indicate which of the unpleasant odors may cause a change of residence, as well as to assess the degree of their impact on the decision to move, taking into account the social and demographic characteristics of residents. New in the article: The novelty of the work was the finding out of the residents’ opinions about the quality of life by accepting the place of residence, taking into account the aspect of odor nuisance. Previous studies on odor nuisance have focused on the emission of odors from individual plants. A novelty of this research is its implementation in an urban area, in which numerous industrial plants are located, with various odors emitted. Research methodology: To assess odor nuisance, a measuring tool developed in accordance with VDI 3883 guidelines was used, based on the latest research results on odor and noise nuisance. The questionnaire was developed based on German experience. Conclusions from the research: The data obtained as a result of the research allow us to state that specific smells are so burdensome that they may cause the necessity to leave the place of residence, because the respondents feel various unpleasant smells that have an adverse impact upon the quality of life that they perceive. A possible need for relocation of domiciles out of the current place of residence due to unpleasant smells would affect the perceptible, specific level of grief—the greater it is, the more attached the residents are to their current place of residence.